Asian Hematology Research Journal

Priapism as the First Manifestation of Chronic Myeloid Leukemia: A Rare Occurrence

Ketan Modak

Department of Clinical Haematology, Haemato-Oncology and Bone Marrow (Stem Cell) Transplant, Christian Medical College, Ludhiana, India.

Naveen John Thomas

Department of Surgery, Christian Medical College, Ludhiana, India.

Partho Mukherjee

Department of Urology, Christian Medical College, Ludhiana, India.

Uma Kant Dutt

Department of Urology, Christian Medical College, Ludhiana, India.

Kanwardeep S. Kwatra

Department of Pathology, Christian Medical College, Ludhiana, India.

M. Joseph John *

Department of Clinical Haematology, Haemato-Oncology and Bone Marrow (Stem Cell) Transplant, Christian Medical College, Ludhiana, India.

*Author to whom correspondence should be addressed.

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Abstract

Priapism is an involuntary, painful erection of the penis for more than 4 hours without any sexual stimulation or ejaculation. It is a urological emergency that requires urgent intervention to prevent erectile dysfunction. We report a case of a young adult who presented to emergency with priapism and was eventually diagnosed to have chronic myeloid leukemia (CML). The priapism resolved with proximal Sacher’s shunt surgery, hydration, hydroxyurea, and tyrosine kinase inhibitors (TKI) after an early diagnosis by the FISH method. Early treatment is the key in managing such patients to reduce the consequences of erectile dysfunction.

Keywords: Priapism, chronic myeloid leukemia, erectile dysfunction

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