Pneumonitis and Encephalitis Associated with Progressing Neoplastic Tumor: A Case Report
Asian Hematology Research Journal,
Page 202-208
Abstract
Purpose: This case report presents a computational analysis of hemorheology in a patient diagnosed with diabetes who experienced encephalitis subsequent to pneumonitis. Hemorheology pertains to the study of blood flow characteristics and plays a critical role in comprehending and addressing various medical ailments. Employing a computational hemorheology model, the outcomes revealed noteworthy irregularities in hemorheology, which potentially contributed to the development of encephalitis following pneumonitis. Moreover, the pre-existing diabetes condition of the patient likely further complicated the hemorheological changes.
Design/Methodology: The study observed abnormal hemorheology in the patient, including alterations in red blood cell deformability, aggregation, and viscosity. The findings suggest that computational modeling of hemorheology provides valuable insights into the mechanisms behind encephalitis subsequent to pneumonitis and holds potential clinical applications in predicting and managing complications associated with these conditions.
Finding: These findings indicate that computational modeling of hemorheology offers valuable insights into the underlying mechanisms of diabetes-related complications and may have significant clinical implications for predicting and managing such complications.
Future Scope: Consequently, this case report emphasizes the significance of comprehending hemorheological alterations in individuals with diabetes and underscores the potential of computational hemorheology in forecasting and addressing complications associated with this condition.
Keywords:
- Hemorheology
- diabetes mellitus
- encephalitis
- pneumonitis
- drug management
How to Cite
References
Goenka A, Michael BD, Ledger E, Hart IJ, Absoud M, Chow G, Kneen R. Neurological manifestations of influenza infection in children and adults: results of a National British Surveillance Study. Clinical Infectious Diseases. 2014;58(6); 775-784.
Taylor GW. Periodontal health and systemic disorders. J Can Dent Assoc. 2002;68(3):188-92.
Sabharwal A, Gomes‐Filho IS, Stellrecht E, Scannapieco FA. Role of periodontal therapy in management of common complex systemic diseases and conditions: An update. Periodontology 2000;78(1): 212-226.
Ergun-Cagli K, Ileri-Gurel E, Ozeke O, Seringec N, Yalcinkaya A, Kocabeyoglu, Dikmenoglu N. Blood viscosity changes in slow coronary flow patients. Clinical Hemorheology and Microcirculation. 2011;47(1):27-35.
Yesudasan S, Averett RD. Recent advances in computational modeling of fibrin clot formation: A review. Computational Biology and Chemistry. 2019;83:107148.
Rychik J, Atz AM, Celermajer DS, Deal BJ, Gatzoulis MA, Gewillig MH. American heart association council on cardiovascular disease in the young and council on cardiovascular and stroke nursing. Evaluation and management of the child and adult with Fontan circulation: A scientific statement from the American Heart Association. Circulation. 2019; 140(6):e234-e284.
Mezil SA, Abed BA. Complication of diabetes mellitus. Annals of the Romanian Society for Cell Biology. 2021;1546-1556.
Cullinan MP, Seymour GJ. Periodontal disease and systemic illness: Will the evidence ever be enough? Periodontology. 2000;62(1):271-286.
Baskurt O. Clinical significance of hemorheological alterations. Handbook of Hemorheology and Hemodynamics. 2007;69:392.
Navaneetharaja N, Griffiths V, Wileman T, Carding SR. A role for the intestinal microbiota and virome in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)?. Journal of Clinical Medicine. 2016;5(6):55.
Yousuf O, Mohanty BD, Martin SS, Joshi PH, Blaha MJ, Nasir K, Budoff MJ. High-sensitivity C-reactive protein and cardiovascular disease: A resolute belief or an elusive link?. Journal of the American College of Cardiology. 2013;62(5):397-408.
Saad H, Soliman HA, Mahmoud B, Moneim AA, Zaky MY. The pathogenic role of oxidative stress, cytokine expression, and impaired hematological indices in diabetic cardiovascular diseases. Inflammation. 2023;46(1): 146-160.
Landon R, Gueguen V, Petite H, Letourneur D, Pavon-Djavid G, Anagnostou F. Impact of astaxanthin on diabetes pathogenesis and chronic complications. Marine Drugs. 2020;18(7):357.
Lumsden AB, Rice TW. Medical management of peripheral arterial disease: A therapeutic algorithm. Journal of Endovascular Therapy. 2006;13 (2_suppl):II-19.
Trimble MR. Anticonvulsant drugs and cognitive function: a review of the literature. Epilepsia. 1987;28:S37-S45.
Feighner JP. Overview of antidepressants currently used to treat anxiety disorders. Journal of Clinical Psychiatry. 1999;60:18-22.
Correll CU, Detraux J, De Lepeleire J, De Hert M. Effects of antipsychotics, antidepressants and mood stabilizers on risk for physical diseases in people with schizophrenia, depression and bipolar disorder. World Psychiatry. 2015;14(2): 119-136.
Brooks DJ. Dopamine agonists: Their role in the treatment of Parkinson's disease. Journal of Neurology, Neurosurgery & Psychiatry. 2000;68(6):685-689.
Moulin DE. Pain in central and peripheral demyelinating disorders: Multiple sclerosis and Guillain-Barre syndrome. Neurologic Clinics. 1998;16(4):889-897.
Szapary L, Horvath B, Marton Z, Alexy T, Demeter N, Szots M, Toth K. Hemorheological disturbances in patients with chronic cerebrovascular diseases. Clinical Hemorheology and Microcirculation. 2004;31(1):1-9.
Fisher M, Meiselman HJ. Hemorheological factors in cerebral ischemia. Stroke. 1991;22(9):1164-1169.
Biller J, Love BB. Ischemic cerebrovascular disease. Neurology in Clinical Practice. 2004;3:1125- 1166.
Kumar S, Behl T, Sachdeva M, Sehgal A, Kumari S, Kumar A, Bungau S. Implicating the effect of ketogenic diet as a preventive measure to obesity and diabetes mellitus. Life Sciences. 2021;264: 118661.
Gorelick PB, Scuteri A, Black SE, DeCarli C, Greenberg SM, Iadecola C, Seshadri S. Vascular contributions to cognitive impairment and dementia: A statement for healthcare professionals from the American heart association/American stroke association. Stroke. 2011;42(9): 2672-2713.
Sharma SK, Chowhan SS. Patient waiting time: It’s impact on hospital outpatient department. International J Scientific Research. 2013;2(3):253-254.
Sharma SK, Chowhan SS. Patient survey to measure the quality of care provided by health care providers in OPD of tertiary care hospitals. Indian Journal of Research. 2013;2(2):208-9.
Chowhan SS. To study the doctor’s perception prescribing practice for cefpodoxime. Think India Journal. 2019;22(35):997-1001.
Timmons JA, Knudsen S, Rankinen T, Koch LG, Sarzynski M, Jensen T, Bouchard C. Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. Journal of Applied Physiology. 2010;108(6):1487-1496.
Afilalo J, Alexander KP, Mack MJ, Maurer MS, Green P, Allen LA, Forman DE. Frailty assessment in the cardiovascular care of older adults. Journal of the American College of Cardiology. 2014;63(8):747-762.
National Collaborating Centre for Women's and Children's Health, & National Institute for Clinical Excellence. Diabetes in pregnancy: Management of diabetes and its complications from preconception to the postnatal period; 2008.
Kim HJ, Lee SJ, Sa S, Bae JH, Song G, Lee CW, Han HW. Safety of COVID-19 vaccines among patients with type 2 diabetes mellitus: Real-world data analysis. Diabetes & Metabolism Journal. 2023;47(3):356-365.
Mishra SK, Chowhan SS, Shah R, Jha N, Shankar PR, Bhandary S, Gorkhaly AP. Knowledge, attitude and practice regarding eye health and eye health services in Nepal; 2019.
Wilkinson DG, Francis PT, Schwam E, Payne-Parrish J. Cholinesterase inhibitors used in the treatment of Alzheimer’s disease: The relationship between pharmacological effects and clinical efficacy. Drugs & Aging. 2004;21:453-478.
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