Asian Hematology Research Journal

Uncommon Presentation of Hodgkin’s Lymphoma: A Case Report

C. E. Nonyelu *

Department of Haematology and Immunology, College of Medicine, University of Nigeria, Ituku-Ozalla, Enugu, Nigeria.

A. J. Madu

Department of Haematology and Immunology, College of Medicine, University of Nigeria, Ituku-Ozalla, Enugu, Nigeria.

I. O. Anigbogu

Department of Haematology and Immunology, College of Medicine, University of Nigeria, Ituku-Ozalla, Enugu, Nigeria.

O. C. Okafor

Department of Morbid Anatomy, College of Medicine, University of Nigeria, Ituku-Ozalla, Enugu, Nigeria.

*Author to whom correspondence should be addressed.

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Abstract

Hodgkin’s lymphoma is a lymphoid malignancy that rarely presents with extranodal involvement and even rarer is presentation involving the central nervous system (CNS). The index patient had a diagnosis of Hodgkin’s lymphoma made from histology and immunophenotyping of the cervical lymph node biopsy. However, involvement of the thoracic vertebrae and epidural with attendant neurological manifestations occurred while on treatment. The central nervous system (CNS) involvement was not biopsied but an impression of Hodgkin’s lymphoma with CNS involvement was made based on primary tissue diagnosis and patient treated as such. He passed on subsequently following complications of chemotherapy and radiotherapy.

Keywords: Hodgkin’s lymphoma, hematolymphoid malignancy, epidural involvement, Intrathecal chemotherapy

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