Asian Hematology Research Journal 2020-07-11T11:38:41+00:00 Asian Hematology Research Journal Open Journal Systems <p style="text-align: justify;"><strong>Asian Hematology Research Journal</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/AHRJ/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of&nbsp;‘Hematology research’. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> Can Plasmapheresis be Useful in the Treatment of Patients with Covid-19? 2020-07-04T08:13:13+00:00 Ali Zahit Bolaman Atakan Turgutkaya İrfan Yavaşoğlu <p>Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) has created a pandemic throughout the world, most notably causing death owing to pneumonia and cytokine storm syndrome. The treatment is highly supportive with no definitive antiviral therapy and aims to alleviate hypercytokinemia in addition to prevent further complications during viral clearance. Therapeutic plasma exchange is the separation of plasma from other blood components and have a potential to clear cytokines which causes the “storm”. Double-Filtration Plasmapheresis is effective of removal of particles huger than 55-60 nm and the method stands the rationale of possibly clearing SARS-CoV-2 (60-140 nm) from blood. In this article we would like to highlight the beneficial potential of plasmapheresis although it’ s an unproven strategy.</p> 2020-07-04T00:00:00+00:00 ##submission.copyrightStatement## Qualitative Phytochemical Screening, Anti-inflammatory and Haematological Effects of Alkaloid Extract of Combretum dolichopetalum Leaves 2020-07-11T11:38:41+00:00 Nwuke P. Chinedu <p><strong>Background:</strong> Inflammation has been implicated in a number of wounds and disease conditions, spurring the search for compounds with anti-inflammatory properties.</p> <p><strong>Aim:</strong> The study investigated the anti-inflammatory potentials and effect of alkaloid extract of <em>Combretum</em> <em>dolichopetalum</em> on haematological parameters of Wistar albino rats.</p> <p><strong>Methodology: </strong>Alkaloids in the leaves were extracted using 10% acetic acid as solvent. The anti-inflammatory potential was investigated using egg-albumin paw edema model, while the haematological effects of the extract was observed on plasma.</p> <p><strong>Results: </strong>Phytochemical screening showed the presence of alkaloids, saponins and tannins in moderate concentration. Alkaloid specific test showed the presence of six classes of alkaloids. Result for anti-inflammatory potentials showed a significant (p&lt;0.05) reduction in paw size of extract treated group compared to negative control. The extract also stabilized haematological parameters compared to negative control.</p> <p><strong>Conclusion:</strong> In conclusion, the study confirms the use of the alkaloid extract of <em>Combretum</em> <em>dolichopetalum</em> leaves in pain management and inflammatory conditions.</p> 2020-07-11T00:00:00+00:00 ##submission.copyrightStatement##